1. the incorrect folding of a protein molecule, resulting in loss of normal function or accumulation of abnormal structures
Usage: technical; biology/biochemistry

1. to fold incorrectly or improperly

Examples

• Protein misfolding is associated with diseases like Alzheimer's and Parkinson's.
• The misfolding of prion proteins can lead to neurodegenerative conditions.
• Heat stress can cause misfolding of cellular proteins.
• Researchers are studying how to prevent misfolding in laboratory settings.
• The enzyme helps correct misfolding before it becomes irreversible.
• Misfolding the map made it difficult to refold it properly.